Does nebivolol improve endothelial dysfunction and will it rescue the reputation of the beta-blockers in the future?
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چکیده
منابع مشابه
Nebivolol: A Novel Beta-Blocker with Nitric Oxide-Induced Vasodilatation
Nebivolol is a novel beta1-blocker with a greater degree of selectivity for beta1-adrenergic receptors than other agents in this class and a nitric oxide (NO)-potentiating, vasodilatory effect that is unique among beta-blockers currently available to clinicians (nebivolol is approved in Europe and is currently under review in the US). A NO-potentiating agent such as nebivolol may have an import...
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Arterial stiffness plays a key role in the pathophysiology of the cardiovascular system. Some indices of arterial stiffness (pulse wave velocity, augmentation index, characteristics of central blood pressure waveform) may be presently calculated and evaluated in the clinical setting. Age and blood pressure are the two major clinical determinants of increased arterial stiffness, while molecular ...
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Beta blockers are used for the management of arterial hypertension and are gold standard treatment for coronary artery disease and heart failure, medical conditions that affect large numbers of older patients and are associated with very high morbidity and mortality rates. Lifelong therapy in primary and secondary prevention (without and with established cardiovascular disease, respectively) is...
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BACKGROUND Vascular endothelial dysfunction may predict future atherosclerosis. Hence, an antihypertensive agent that reverses endothelial dysfunction and lowers blood pressure might improve the prognosis of patients with hypertension. We hypothesized that nebivolol, a vasodilating beta-blocker, could improve endothelial dysfunction. We tested this hypothesis by comparing the effects of nebivol...
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ورودعنوان ژورنال:
- Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
دوره 7 4 شماره
صفحات -
تاریخ انتشار 2007